After an individual is diagnosed with Multiple endocrine neoplasia type 2 (MEN2) or a mutation or change is found in the RET gene, other family members are at risk to have MEN2. First-degree relatives (siblings, children, and parents) have a 50% chance to have the same genetic change. Second-degree relatives (nieces/nephews, aunts/uncles, grandparents, grandchildren, and half siblings) have a 25% chance to have the same gene mutation. It is recommended that relatives be informed of their risk. Whether testing is right for them is a personal decision. Also, RET testing is not generally recommended for people under 18 years of age.
Genetic counselors can help explain autosomal dominant inheritance and family members who may be at risk to have MEN2. They can also help identify who may want to consider genetic testing for the RET gene. In the US, a genetic counselor can be located at the Find a Genetic Counselor website on the National Society of Genetic Counselor website.
Other Questions About Multiple endocrine neoplasia 2
- Who else in my family should have testing for Multiple endocrine neoplasia type 2?
- Where do I find other people with Multiple endocrine neoplasia type 2?
- Where can I get financial help for Multiple endocrine neoplasia type 2?
- Where can caregivers of people with Multiple endocrine neoplasia type 2 get support?
- What types of doctors will I see for treatment of Multiple endocrine neoplasia 2?
