If you have a positive test result in a gene that can cause familial Alzheimer Disease, other family members may be at risk to have the same genetic change. First-degree relatives (siblings, children, and parents) may have a 50% chance to have the same genetic change. Second-degree relatives (nieces/nephews, aunts/uncles, grandparents, grandchildren, and half siblings) may have a 25% chance to have the same genetic change. Genetic testing is a personal decision. Not everyone at risk for a genetic condition chooses to have genetic testing. Some people will choose to proceed with the testing and some people will not. Each individual must consent to having genetic testing.
Other Questions About Alzheimer disease
- Who else in my family should I test for familial Alzheimer Disease?
- Where do I find other people with Alzheimer Disease?
- What’s my risk to develop Alzheimer Disease if my parent had the disease?
- What is the risk to develop Alzheimer Disease if there is no or limited family history of the disease?
- What is the likelihood that someone has familial Alzheimer Disease?