Since most cases of Prader-Willi syndrome are caused by a random change to the affected individual’s genetic material, it is unlikely that other family members will be affected. However, there are rare cases in which Prader-Willi syndrome can be inherited from a change to a parent’s genetic material. Depending upon the type of genetic change in the affected individual, testing of siblings and/or parents may be recommended. For more information about this, speak with a Medical Geneticist or a [link url="www.nsgc.org” target=”_blank”>Genetic Counselor.